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KMID : 1025520130550030165
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Journal of Animal Science and Technology
2013 Volume.55 No. 3 p.165 ~ p.171
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Comparison of Breeding Value by Establishment of Genomic Relationship Matrix in Pure Landrace Population
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Lee Jun-Ho
Cho Kwang-Hyun
Cho Chung-Il
Park Kyung-Do
Lee Deuk-Hwan
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Abstract
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Genomic relationship matrix (GRM) was constructed using whole genome SNP markers of swine and genomic breeding value was estimated by substitution of the numerator relationship matrix (NRM) based on pedigree information to GRM. Genotypes of 40,706 SNP markers from 448 pure Landrace pigs were used in this study and five kinds of GRM construction methods, G05, GMF, GOF, GOF* and GN, were compared with each other and with NRM. Coefficients of GOF considering each of observed allele frequencies showed the lowest deviation with coefficients of NRM and as coefficients of GMF considering the average minor allele frequency showed huge deviation from coefficients of NRM, movement of mean was expected by methods of allele frequency consideration. All GRM construction methods, except for GOF*, showed normally distributed Mendelian sampling. As the result of breeding value (BV) estimation for days to 90 kg (D90KG) and average back-fat thickness (ABF) using NRM and GRM, correlation between BV of NRM and GRM was the highest by GOF and as genetic variance was overestimated by GOF*, it was confirmed that scale of GRM is closely related with estimation of genetic variance. With the same amount of phenotype information, accuracy of BV based on genomic information was higher than BV based on pedigree information and these symptoms were more obvious for ABF then D90KG. Genetic evaluation of animal using relationship matrix by genomic information could be useful when there is lack of phenotype or relationship and prediction of BV for young animals without phenotype.
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KEYWORD
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Genomic selection, Genomic relationship matrix, Genomic breeding value, SNP markers, Landrace
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